Which of the following are key ethical considerations in human subject research?

Informed consent and risk-benefit analysis are fundamental ethical considerations in human subject research. Informed consent ensures that participants are fully aware of the nature of the research, including its purposes, procedures, potential risks, and benefits, allowing them to make educated decisions about their participation. This process fosters respect for the autonomy of individuals, affirming their right to participate voluntarily without coercion.

Risk-benefit analysis is equally crucial, as it involves evaluating the potential risks to participants against the expected benefits of the research. This analysis helps ensure that the research is designed to minimize harm while maximizing potential benefits, not just for the participants but for society as a whole. These ethical considerations are essential for protecting the rights and welfare of human subjects and ensuring that research is conducted responsibly.

The other choices do not align with ethical standards. For instance, maximizing profit from research outcomes can lead to ethical dilemmas that compromise participant safety or data integrity. Similarly, minimizing participant involvement may disregard the importance of obtaining comprehensive data, while focusing solely on the researcher's objectives overlooks the need to consider participants' rights and well-being. Emphasizing informed consent and risk-benefit analysis reflects a commitment to conducting ethical research that upholds the dignity and rights of individuals involved.