What are Jojo's chances of inheriting sickle cell disease?

To determine Jojo's chances of inheriting sickle cell disease, it is important to first understand the genetics involved in this condition. Sickle cell disease is inherited in an autosomal recessive manner, meaning that a person must inherit two copies of the sickle cell gene (one from each parent) to express the disease.

Typically, each parent can contribute either a normal gene or a gene for sickle cell. If both parents are carriers (meaning they each have one normal gene and one sickle cell gene), there is a 25% chance with each child that they will inherit two sickle cell genes (one from each parent) and thus have sickle cell disease. Consequently, if Jojo's parents do not carry the sickle cell trait or gene (both are normal), then Jojo would have no chance of inheriting the disease.

In this scenario, if the correct answer indicates that Jojo has a 0% chance of inheriting sickle cell disease, it suggests that both of Jojo's parents do not carry the sickle cell gene, meaning they each possess two normal alleles. Therefore, Jojo will inherit normal genes from both parents, resulting in a 0% probability that Jojo will inherit sick